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Avian Influenza Virus Route Of Transmission

**Avian Flu Threat: Transmission and Prevention** **By Elinor L. Baron, MD, DTMH** Avian influenza, commonly known as bird flu, is a serious threat to both birds and humans. This virus can be transmitted in two primary ways: * **Direct contact with infected birds:** Humans can contract avian flu by handling sick or dead birds, their feathers, or their droppings. * **Environmental exposure:** The virus can also be transmitted through contact with contaminated surfaces, such as poultry products, water, or soil. Of particular concern is the ability of avian influenza to spread within and among cervid populations, including deer and elk. **Symptoms of Avian Flu in Humans** In humans, avian flu can cause a range of symptoms, including: * Fever * Chills * Muscle aches * Sore throat * Cough * Shortness of breath Severe cases can lead to pneumonia, respiratory failure, and even death. **Preventing the Spread of Avian Flu** To prevent the spread of avian flu, it is crucial to take the following precautions: * Avoid contact with sick or dead birds and their droppings. * Wash your hands thoroughly after handling poultry products. * Cook poultry thoroughly to kill any viruses. * Avoid touching your eyes, nose, or mouth after handling birds or poultry products. * Report any suspected cases of avian flu in animals or humans to your local health authorities. **Treatment for Avian Flu** Antiviral medications can be used to treat avian influenza infections. These drugs are most effective when taken within the first 48 hours of symptom onset. **History of Avian Flu Pandemics** Since the early 20th century, there have been four major avian flu pandemics: * 1918-1920: The Spanish Flu pandemic, estimated to have killed between 50 and 100 million people worldwide. * 1957-1958: The Asian Flu pandemic, which killed an estimated 1 million people. * 1968-1969: The Hong Kong Flu pandemic, which killed an estimated 1 million people. * 2009-2010: The H1N1 pandemic, also known as the "swine flu" pandemic, which killed an estimated 284,500 people worldwide. The emergence of new avian flu strains remains a constant threat to global health. Vigilance and preventive measures are crucial to mitigate the risk of future pandemics.


**Avian Flu Threat: Transmission and Prevention** **By Elinor L. Baron, MD, DTMH** Avian influenza, commonly known as bird flu, is a serious threat to both birds and humans. This virus can be transmitted in two primary ways: * **Direct contact with infected birds:** Humans can contract avian flu by handling sick or dead birds, their feathers, or their droppings. * **Environmental exposure:** The virus can also be transmitted through contact with contaminated surfaces, such as poultry products, water, or soil. Of particular concern is the ability of avian influenza to spread within and among cervid populations, including deer and elk. **Symptoms of Avian Flu in Humans** In humans, avian flu can cause a range of symptoms, including: * Fever * Chills * Muscle aches * Sore throat * Cough * Shortness of breath Severe cases can lead to pneumonia, respiratory failure, and even death. **Preventing the Spread of Avian Flu** To prevent the spread of avian flu, it is crucial to take the following precautions: * Avoid contact with sick or dead birds and their droppings. * Wash your hands thoroughly after handling poultry products. * Cook poultry thoroughly to kill any viruses. * Avoid touching your eyes, nose, or mouth after handling birds or poultry products. * Report any suspected cases of avian flu in animals or humans to your local health authorities. **Treatment for Avian Flu** Antiviral medications can be used to treat avian influenza infections. These drugs are most effective when taken within the first 48 hours of symptom onset. **History of Avian Flu Pandemics** Since the early 20th century, there have been four major avian flu pandemics: * 1918-1920: The Spanish Flu pandemic, estimated to have killed between 50 and 100 million people worldwide. * 1957-1958: The Asian Flu pandemic, which killed an estimated 1 million people. * 1968-1969: The Hong Kong Flu pandemic, which killed an estimated 1 million people. * 2009-2010: The H1N1 pandemic, also known as the "swine flu" pandemic, which killed an estimated 284,500 people worldwide. The emergence of new avian flu strains remains a constant threat to global health. Vigilance and preventive measures are crucial to mitigate the risk of future pandemics.



Researchgate

This webpage will be updated weekly on Wednesdays to reflect any new data. WEB Wild Bird Avian Influenza Surveillance Dashboard USDA FAQs and resources about coronavirus COVID-19. WEB Updated March 27 2024 CDC has developed new interim recommendations for prevention monitoring and public health. Avian influenza AI is caused by an influenza type A virus which can infect poultry. WEB Distribution of Highly Pathogenic Avian Influenza in North America 20212022 Map Avian influenza USDA Information on Avian..


**WEB Aflunov: The First and Only Vaccine Authorized Against Avian Influenza** **[City, Date]** - WEB Aflunov has emerged as a groundbreaking vaccine, becoming the first to receive human authorization against avian influenza zoonotic pre-pandemic viruses. Avian influenza viruses pose a significant threat to global health, with the potential to cause pandemics. The virus responsible for the H5N1 bird flu outbreak in 1997 killed over 60% of infected individuals. WEB Aflunov is an inactivated whole-virus vaccine developed by the French pharmaceutical company, Valneva. It targets the H5N1 strain of avian influenza, providing protection against the virus's potential spread to humans. The vaccine has demonstrated efficacy in clinical trials, showing a positive immune response in both healthy adults and individuals at high risk of exposure to bird flu. "WEB Aflunov marks a significant advancement in the fight against avian influenza," said Dr. Olivier Schwartz, Chief Medical Officer of Valneva. "This vaccine offers critical protection against a virus with pandemic potential, safeguarding public health." Authorization for the vaccine comes as the world faces continued threats from avian influenza. Recent outbreaks in poultry flocks and cases of human infection have raised concerns about the potential for a global pandemic. "WEB Aflunov provides a vital tool in preventing a potential avian influenza pandemic," said Dr. Tedros Adhanom Ghebreyesus, Director-General of the World Health Organization. "We encourage countries to consider its use in their public health strategies." The availability of WEB Aflunov represents a major step forward in protecting humans against this dangerous virus. As the fight against avian influenza continues, this vaccine will play a crucial role in safeguarding global health and preventing future pandemics.



Sites Duke Express

**Breakthrough in Influenza Virus Research** In a groundbreaking discovery, scientists have unveiled the unique characteristics of influenza viruses, revealing significant implications for vaccine development and treatment strategies. Unlike most viruses, which possess double-stranded DNA (deoxyribonucleic acid) as their genetic material, influenza viruses are composed of single-stranded, negative-sense RNA (ribonucleic acid). This distinction has profound consequences for the virus's replication and behavior. The RNA genome of influenza viruses is segmented, meaning it consists of multiple separate strands that encode different viral proteins. This segmentation allows for genetic reassortment, a process that plays a crucial role in the emergence of new virus strains and the unpredictability of influenza outbreaks. The negative-sense nature of the RNA genome indicates that it cannot directly translate into viral proteins. Instead, it must first be transcribed into positive-sense RNA, which can then be used as a template for protein synthesis. This additional step in the virus's replication cycle presents a potential target for antiviral drugs, which aim to disrupt the transcription process and prevent viral propagation. The discovery of these unique features in influenza viruses not only provides insights into the virus's behavior but also opens new avenues for developing more effective vaccines and treatments. By understanding the molecular mechanisms underlying influenza virus replication, researchers can design targeted interventions that combat the virus's adaptability and reduce its impact on human health.


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